Hospital for Special Surgery Study Shows AI Tool Effectively Prepares Patients for Joint Replacement Surgery

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DALLAS--(BUSINESS WIRE)--Oct 24, 2025--

Preparing for orthopedic surgeries such as hip or knee replacement can be stressful for patients, who often have many questions and concerns about what to expect. Hospital for Special Surgery (HSS) presented new findings at the American Association of Hip and Knee Surgeons annual meeting suggesting that artificial intelligence (AI) is a powerful educational tool that can help patients feel prepared and supported before and after surgery.

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Hospital for Special Surgery Study Shows AI Tool Effectively Prepares Patients for Joint Replacement Surgery

HSS researchers piloted and evaluated a custom-tailored AI (CTAI) platform that was trained on patient education content developed and approved by HSS surgeons. They found that patients were able to easily access and interact with the chat bot, which provided on-demand, personalized, accurate information about their surgery.

“Our study showed that most patients found the technology easy to use and helpful in making them feel ready and confident going into surgery,” says Eytan M Debbi, MD, PhD, hip and knee replacement surgeon at HSS and senior author of the study.

HSS investigators partnered with Aidify to develop the CTAI agent to address patient questions related to total joint arthroplasty (TJA) procedures such as hip and knee replacement surgery. Orthopedic surgeons at HSS trained the chat bot with their specific surgical protocols so that patients could receive personalized content that reflects their expertise.

Patients undergoing orthopedic procedures frequently face confusion and anxiety before surgery and are often dissatisfied with printed educational materials that can be hard to understand and not tailored to their needs. However, patients in the study gave Aidify high marks for responses that were useful, understandable, and complete.

“This platform can provide round-the-clock access to reliable, doctor-specific guidance and reduce the risk of getting inaccurate or irrelevant information from other general-purpose tools like Google or Chat GPT,” says Karlos Zepeda, DO, clinical research coordinator at HSS and lead author of the study.

The study included 40 patients scheduled to undergo TJA at HSS. Among the 32 patients who used the chat bot, about 85% said they understood the responses to their questions and 75% reported that it helped them feel well prepared for surgery. More than 80% of patients stated they would recommend the platform to others.

“I think patients get a lot of comfort knowing they have access to the chat bot because it gives them the sense that they can always be in contact with our office and get their questions answered whenever they need it,” explains Dr. Debbi.

Patients in the study were emailed a link to the interactive platform trained on information about the surgery they were going to have. They could then type their questions into the chat bot and get responses instantly.

The CTAI tool addressed a wide range of questions that focused mostly on concerns leading up to surgery and on recovery. These included activity guidelines, medications, what to expect after surgery, dietary guidance, pain management, wound care, and potential complications. The bulk of patients’ questions came in before surgery, while the number and frequency of questions diminished after surgery.

“Our findings show that CTAI improves patients’ health literacy, which enables more understanding, confidence, and preparedness before surgery,” says Dr. Zepeda. “This directly impacts patients’ overall satisfaction and care experience.”

The most unexpected finding, according to the authors, was the number of study participants who were able to access and navigate the platform. Most people who need TJA are over the age of 55, so there was a concern that older patients in the study might have some difficulty using AI technology.

“I was surprised that older patients were able to deal with the technology as easily as they did and be as satisfied as they were with it,” observes Dr. Debbi, who adds that some patients preferred interacting with the chat bot over their surgeon. “Surgeons cannot be available to patients 24 hours a day, but AI can review things with multiple patients at a time, whenever and as many times as they want without physician burnout, so that’s a huge benefit.”

CTAI streamlines communication and reduces the burden of repetitive or nonurgent questions on busy clinical staff. “The power of AI can extend the surgeon and their team to more patients by efficiently addressing patient concerns in real time and ensuring that they consistently receive the right information exactly as their surgeon intended,” explains Dr. Zepeda.

If the platform doesn’t know the answer to a question or there is an emergency, it will prompt the patient to contact their doctor’s office, call 911, and/or use the My Chart/Epic patient portal to send in their question to the appropriate provider, who would be notified of the issue and respond or escalate as needed.

“We are still in the research phase and very carefully monitor every question that comes in to make sure nothing slips through the cracks,” notes Dr. Zepeda.

The study authors agree that their findings support continued refinement of CTAI as a tool to improve the delivery of patient education and care at HSS, but more research is needed to expand its use. For example, the technology does not currently have access to specific patient information.

“Only when we are confident in the technology and that patient information is secure will we enable AI to fully interact with patients’ electronic medical record and integrate it as standard of care at HSS,” says Dr. Debbi. “The potential of CTAI is unlimited. The sky’s the limit and we’re just scratching the surface right now.”

About HSS

HSS is the world’s leading academic medical center focused on musculoskeletal health. At its core is Hospital for Special Surgery, nationally ranked No. 1 in orthopedics (for the 16th consecutive year), No. 3 in rheumatology by U.S. News & World Report (2024-2025), and the best pediatric orthopedic hospital in NY, NJ and CT by U.S. News & World Report “Best Children’s Hospitals” list (2025-2026). In a survey of medical professionals in more than 20 countries by Newsweek, HSS is ranked world #1 in orthopedics for a fifth consecutive year (2025). Founded in 1863, the Hospital has the lowest readmission rates in the nation for orthopedics, and among the lowest infection and complication rates. HSS was the first in New York State to receive Magnet Recognition for Excellence in Nursing Service from the American Nurses Credentialing Center five consecutive times. An affiliate of Weill Cornell Medical College, HSS has a main campus in New York City and facilities in New Jersey, Connecticut and in the Long Island and Westchester County regions of New York State, as well as in Florida. In addition to patient care, HSS leads the field in research, innovation and education. The HSS Research Institute comprises 20 laboratories and 300 staff members focused on leading the advancement of musculoskeletal health through prevention of degeneration, tissue repair and tissue regeneration. In addition, more than 200 HSS clinical investigators are working to improve patient outcomes through better ways to prevent, diagnose, and treat orthopedic, rheumatic and musculoskeletal diseases. The HSS Innovation Institute works to realize the potential of new drugs, therapeutics and devices. The HSS Education Institute is a trusted leader in advancing musculoskeletal knowledge and research for physicians, nurses, allied health professionals, academic trainees, and consumers in more than 165 countries. The institution is collaborating with medical centers and other organizations to advance the quality and value of musculoskeletal care and to make world-class HSS care more widely accessible nationally and internationally. www.hss.edu.

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SOURCE: Hospital for Special Surgery

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PUB: 10/24/2025 07:00 AM/DISC: 10/24/2025 07:00 AM

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